What stage is indicative of significant signs of decay in a body?

The stage that signifies significant signs of decay in a body is the stage known as moderate decomposition. During this phase, the process of decay has advanced to a point where the body has begun to undergo various changes visible to the trained observer. This can include the breakdown of tissues and the development of odors associated with the decay process. Additionally, notable changes such as discoloration and the presence of insects and their larvae can be observed, which contributes to the understanding of the timeframe since death and overall state of decay.

In contrast, the other stages mentioned, such as maggot masses and adipocere, refer to more specific conditions or developments in the decomposition process. Maggot masses indicate the presence of insect activity, which often occurs in the early stages of decomposition when fresh carcasses attract flies. Skeletonization represents a much later stage after most organic material has decomposed, leading to the bones being the primary remaining structure. Adipocere involves the transformation of body fat into a waxy substance under certain conditions and also suggests a distinct and later phase of decay. Thus, moderate decomposition is the most accurate choice to indicate significant signs of decay overall.